Patients’ beliefs about the effectiveness of their treatments are key to the success of any intervention. However, since these beliefs are usually formed by sequentially accumulating evidence in the form of the covariation between the treatment use and the symptoms, it is not always easy to detect when a treatment is actually working. In Experiments 1 and 2, we presented participants with a contingency learning task in which a fictitious treatment was actually effective to reduce the symptoms of fictitious patients. (...) However, the base-rate of the symptoms was manipulated so that, for half of participants, the symptoms were very frequent before the treatment, whereas for the rest of participants, the symptoms were less frequently observed. Although the treatment was equally effective in all cases according to the objective contingency between the treatment and healings, the participants’ beliefs on the effectiveness of the treatment were influenced by the base-rate of the symptoms, so that those who observed frequent symptoms before the treatment tended to produce lower judgments of effectiveness. Experiment 3 showed that participants were probably basing their judgments on an estimate of effectiveness relative to the symptom base-rate, rather than on contingency in absolute terms. Data, materials, and R scripts to reproduce the figures are publicly available at the Open Science Framework. (shrink)

The acquisition and evolution of speech production, discourse and communication can be negatively impacted by brain malformations. We describe, for the first time, a case of developmental dynamic dysphasia (DDD) in a right-handed adolescent boy (subject D) with cortical malformations involving language-eloquent regions (inferior frontal gyrus) in both the left and the right hemispheres. Language evaluation revealed a markedly reduced verbal output affecting phonemic and semantic fluency, phrase and sentence generation and verbal communication in everyday life. Auditory comprehension, repetition, naming, (...) reading and spelling were relatively preserved, but executive function was impaired. Multimodal neuroimaging showed a malformed cerebral cortex with atypical configuration and placement of white matter tracts bilaterally and abnormal callosal fibers. Dichotic listening showed right hemisphere dominance for language and functional magnetic resonance imaging (fMRI) additionally revealed dissociated hemispheric language representation with right frontal activation for phonology and bilateral dominance for semantic processing. Moreover, subject D also had congenital mirror movements (CMM), defined as involuntary movements of one side of the body that mirror intentional movements of the other side. Transcranial magnetic stimulation and fMRI during voluntary unimanual (left and right) hand movements showed bilateral motor cortex recruitment and tractography revealed a lack of decussation of bilateral corticospinal tracts. Genetic testing aimed to detect mutations that disrupt the development of commissural tracts correlating with CMM (e.g., Germline DCC mutations) was negative. Overall, our findings suggest that DDD in subject D resulted from the underdevelopment of the left inferior frontal gyrus with limited capacity for plastic reorganization by its homologous counterpart in the right hemisphere. Corpus callosum anomalies probably contributed to hinder interhemispheric connectivity necessary to compensate language and communication deficits after left frontal involvement. (shrink)

Background: Serious games have shown positive results in increasing motivation, adherence to treatment and strengthening the therapeutic alliance in multiple psychiatric disorders. In particular, patients with impulse control disorders and other disorders in which the patient suffers from inhibitory control deficits have been shown to benefit from serious games.Aim: The aim of this study was to describe the characteristics and to evaluate the usability of a new serious videogame, e-Estesia. This serious videogame was designed to improve emotion regulation in patients (...) with gambling disorder. Preliminary results from a pilot sample are also reported.Method: A pilot sample of 26 patients undergoing treatment for GD was recruited. Participants used e-Estesia on a tablet, which was connected to a thoracic band that sent heart rate and heart rate variability data to the videogame platform in order to provide biofeedback. The System Usability Scale was completed by patients to determine the usability of e-Estesia.Results and Discussion: e-Estesia performed comparatively well for all the explored groups. Around 84.6% of the patients endorsed that it was easy to use. Female patients with GD presented higher HRV during the use of the serious videogame compared to men. (shrink)

QUESTIONS DE METHODE I. Au contraire de Sartre qui, a partir de quelques elements cueillis dans les ecrits de HusserI concernant la conscience ima geante, a bllti sa propre doctrine de!'imagination, nous nous proposons de reconstituer, a partir de ces m~mes elements, ce qu'on pourrait appeler la theort:e husserlienne de l'imagination, c'est-a-dire la theorie que HusserI eut lui-m~me construite, s'il avait reuni en une synthese les elements qu'il a laisses epars. Une entreprise de ce genre est toujours delicate et souleve (...) des prob!emes difficiles - a commencer par celui de sa legitimite. N ous ecartons d'emblee l'objection d'ordre general qui contesterait Ie droit de systematiser dans l'reuvre d'un auteur ce que lui-m~me a laisse disperse et eventuellement inacheve. Par un tel scrupule, on sacrifie sans doute a la rigueur historique mais on est beaucoup moins soucieux de penetrer une pensee dans son dynamisme in terne et profond et, en derniere analyse, on protege les droits de l'archeologie mais non pas ceux de la culture et de son progreso Nous pensons a une difficulte beaucoup plus serieuse; de sa so lution depend l'attitude a adopter en face des textes dont nous devons nous servir dans notre etude. Nous utilisons des ouvrages qui couvrent la totalite de la car riere philosophique de HusserIl. (shrink)

Procurou-se, e esse foi o objetivo essencial, que este volume fosse marcado pelo discurso questionador e crítico de historiadores, de filósofos, de especialistas da ciência política, das ideias, do direito, da economia, da educação, da comunicação, da informação, das ciências, das artes. Surgiram assim interpretações, quadros, configurações e reconfigurações, ângulos de análise diversificados que fomentarão, por certo, uma reflexão viva dos leitores. É fundamental — continua a sê-lo — repensar e questionar campos temáticos à luz das análises teóricas e concetuais, (...) mas também dos processos, das dinâmicas, das relações, das potencialidades explicativas da nossa contemporaneidade. É assim que se entende este livro, com muitas contribuições, que vêm propiciar e enriquecer a reflexão sobre Outros Combates pela História. Combates pela História é, como se sabe, o título de um livro famoso de Lucien Febvre dos anos cinquenta. Através de uma recomposição, de novo se deu importância a todas as modalidades da História, mantendo, todavia, o sentido do rigor que era algo perseguido nos «combates pela História». Quer-se, pois, analisar o sentido da História, nas suas várias áreas. Contudo, ao propor-se este tema, não se desejou que os autores apresentassem tanto as suas investigações nas suas áreas próprias — embora elas estivessem subentendidas e devessem ser expressas —, mas que refletissem sobre o seu sentido no âmbito da História entendida como Ciência Social e Humana. Para tal, desejou-se que discutissem o objeto e o método da História das diversas áreas, equacionando os seus vários problemas. Foi isso que também sucedeu — estamos disso convencidos. Mas será o leitor, melhor do que ninguém, a ajuizá-lo. (shrink)

Louise Weiss (1893 – 1983) percorre, em múltiplas viagens, o Ocidente europeu, a América, as longínquas paragens do Oriente, o continente africano. A sua obra, em particular as Mémoires d’une Européenne, revela-se um testemunho eloquente de sua força anímica e do olhar atento e crítico das décadas vividas no século XX. É no espaço e no tempo das suas múltiplas viagens que Weiss diagnostica e espelha a relação de Alteridade Ocidente / Oriente, entre a Europa e o Outro. A vida (...) e a acção militante no curso de sua longa vida centrou-se em três pólos nucleares: combate pela paz, combate pelo voto feminino e combate pela construção da Europa.É nesta luta incessante que Louise Weiss – a Europeia cumpria o lema que a norteava – partic­ipar na aventura do seu século. (shrink)

Na análise do equilíbrio trabalho-família, tem-se salientado o efeito de extravasamento (spillover). Neste estudo, realizado por entrevista semiestruturada a uma amostra de 102 mães portuguesas (incluindo 79 sinalizadas por mau trato e negligência), abordam-se os impactos da situação profissional da..

Este artículo examina las novelas El espíritu de mis padres sigue subiendo en la lluvia (2011), de Patricio Pron, y Yo la quise (2019), de Josefina Giglio, con énfasis en las formas de narrar, desde donde se analiza una tensión entre la experiencia vivida y su devenir en un artificio transitando la relación entre literatura y memoria desde la perspectiva de la generación nacida durante la dictadura argentina. Así, el estudio recupera el concepto de espacio biográfico postulado por Arfuch, articulado (...) con la noción de plan perteneciente a Deleuze-Guattari y la de cronotopo de Bajtín. En la novela de Pron, el retorno de un joven escritor a la Argentina constituye el punto de inflexión a partir del cual se encabalga la historia de la desaparición de Alberto (2008), la de Alicia desaparecida en Tucumán (1976), y la de los padres del escritor, militantes de la Guardia de Hierro. En Giglio, la arquitectónica entreteje la historia del personaje Yo, un escritor reconocido, quien se halla frente a la imposibilidad de transformar en materialidad ficcional una relación amorosa de la juventud; la de Ella, una militante del partido comunista; y la de la Nena, quien relata la convivencia con su hermano y sus abuelos después de la desaparición de sus padres. Ambas novelas remiten a las preguntas sobre cómo narrar la experiencia y bajo qué formas enunciar para hacer visible el acontecimiento histórico. El artículo contribuye al campo de los estudios de la memoria y sus lenguajes artísticos, la literatura de la generación nacida en 1970.. (shrink)

Ortega no estudió de manera concreta el tema de la religión. Sin embargo, a lo largo de su obra, encontramos muchas y variadas referencias a cuestiones religiosas. Parte de ellas se refieren, sobre todo en su juventud, a un personal modo de concebir la religión: como afirmación de la vida, respeto y fidelidad a uno mismo y a su circunstancia. Además de las fuentes de inspiración en Goethe o Renan, es indispensable, para comprender esta concepción, contar con las problemáticas religiosas (...) de la época. Éstas se enclavan en la circunstancia por excelencia del pensamiento de Ortega: el problema de España, y su atraso científico y cultural respecto a Europa. (shrink)

Harmful but culturally cherished practices often endure in spite of the damages they cause. Meat consumption is increasingly becoming one of such cases and may provide an opportunity from which to observe these phenomena. Growing evidence indicates that current and projected production and consumption patterns are important contributors to significant environmental problems, public health degradation, and animal suffering. Our aim is to contribute to a further understanding of the psychological factors that may hinder or promote personal disposition to change food (...) habits to benefit each of these domains. Drawing from previous evidence, this study explores the proposition that some consumers are motivated to resort to moral disengagement strategies when called upon to consider the impacts of their food habits. Data were collected from six semi-structured focus groups with a sample of 40 participants. Although affirming personal duties towards preserving the environment, promoting public health, and safeguarding animal welfare, participants did not show personal disposition to change their meat consumption habits. Several patterns of response that resonate with the principles of moral disengagement theory were observed while discussing impacts and the possibility of change. Results seem to support the proposition that the process of moral disengagement may play a role in hindering openness to change food habits for the benefit of the environment, public health, and animals, and point towards the relevance of further exploring this approach. (shrink)

Firstly we consider the new results about enzymatic capabilities in the RNA. In this framework we analyse the sequence-folding duality as a precursor of the genotype/phenotype duality. We discuss then which are the evolutive potentialities and limitations for a system with the absence and the presence of a nucleic acid to proteins translator code. We study the arise of the code in the living systems as a form of deep interlooking between the logic of the machinery and its hardware, discussing (...) some problems that abstract modelization of this process implies. Finaly we propose to redefine the informational vocabulary usually employed in Molecular Biology. (shrink)

The vertebrate spleen has important functions in immunity and haematopoiesis, many of which have been well studied. In contrast, we know much less about the mechanisms governing its early embryonic development. However, as a result of work over the past decade‐mostly using knockout mice–‐significant progress has been made in unravelling the genetic processes governing the spleen's early development. Key genetic regulators, such as Tlx1 and Pbx1, have been identified, and we know some of the early transcriptional hierarchies that control the (...) early patterning and proliferation of the splenic primordium. In mouse and humans, asplenia can arise as a result of laterality defects, or the spleen can be absent with no other discernible abnormalities. Surprisingly, given the spleen's diverse functions, asplenic individuals suffer no major haematopoietic or immune defects apart from a susceptibility to infection with encapsulated bacteria. Recent evidence has shed light on a previously unknown role of the spleen in the development and maintenance of specific B cell populations that are involved in the initial response to infection caused by encapsulated bacteria. The lack of these populations in asplenic mice and humans may go some way to explaining this susceptibility. BioEssays 29: 166–177, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

La obra de René Girard está salpicada de críticas al humanismo y a los humanistas. En este estudio nos preguntamos en primer lugar qué es el humanismo, haciéndonos cargo de la problemática historiográfica. Presentamos el contraste existente entre los tópicos e ideales humanistas y las ideas que se derivan de la teoría mimética. Estudiamos las críticas explícitas de Girard a los humanistas y, por último, adoptamos una perspectiva que permite calificarlo a él mismo como un humanista.

O objectivo deste nosso breve estudo sobre o texto de Eduardo Soveral “Análises gnosiológicas” é o de avaliar a originalidade e o valor da reflexão do professor portuense, no âmbito do pensamento português contemporâneo. Notamos, por um lado, que a sua abordagem gnosiológica é o ponto de partida para uma fundamentação do saber, relativamente às várias áreas disciplinares da filosofia. Por outro, constatamos também que a sua reflexão toma como modelo de especulação filosófica e gnosiológica o seu mestre e professor (...) conimbricense Arnaldo de Miranda Barbosa, com o qual Eduardo Soveral manterá um vivo e aceso debate ao longo da sua actividade filosófica e de docência na Faculdade de Letras da Universidade do Porto. (shrink)

The symbols of the Feminine throughout the dystopian novel The Handmaid’s Tale are the object of study of the article. It is argued that feminine symbology is a unifying thread that makes possible an analysis of the main features of dystopian societies and the possibility of a critical dystopia. The category of analysis is the symbol understood from the perspective of Ricoeur’s hermeneutics of symbols, which proposes that the understanding of a text should be based on what they pretend to (...) say. Therefore, the symbols of the Feminine make possible the resistance within dystopian regimes, and without resistance there is no dystopia. As a result, it is possible through the symbols of the Feminine to interpret the main features of dystopias and, particularly, to develop the possibility of a feminist critical dystopia. (shrink)

Advances in perinatology have permitted the survival of fragile neonates. Quality of life has been considered a key element in medical decision-making. In this review we analyse the role of Q...

El artículo analiza el rol que cumple la confianza en la construcción de la realidad social, argumentando que constituye uno de sus componentes esenciales. Lo es porque hace posible el nacimiento, permanencia y reconocimiento colectivo de las instituciones, así como su iteración y organización en subsistemas.

In order to present the incidence of the dynamic turn in the logic of scientific research, we begin with a section, in this article, that deals with logical games as triggers of this dynamic turn in contemporary logic, together with the program of logical dynamics of information and interaction. We briefly introduce the main characteristics of the logic favorable to independence and the game-theoretical semantics, of dialogical logic, as well as the essential elements of this program. Although from any of (...) these points of view we have a list of logical tools to deal with more clearly epistemological issues, we highlight the role of dynamic epistemic logic, to which we dedicate the following section. There follows another one in which we enter the logical studies of abduction as one of the fundamental problems of contemporary epistemology and, in a new section, in terms of the theoretical constructs of the preceding sections, we present and explain a phenomenon that emerged in the field of linguistics, the case of the discovery of the Amazonian language pirahã, which should be considered an anomaly within the framework of the Chomskian theory. (shrink)

In this paper we examine the idea of beatitudo in Duns Scotus. We begin with the Quaestiones super libros metaphysicorum, where the Doctor Subtilis presents a conception of the act of intellective knowledge through the natural meaning of beatitude. Taking up the famous incipit of the Metaphysics, Duns Scotus develops the idea of a maximum desiderium and a maxima scientia as a way of human and natural perfection. In conceiving this desiderium naturale as form of ultimate realization, he sees it (...) as similar to the knowledge of immaterial substances in statu viae. His definition of beatitudo also disagrees with the Thomist doctrine, developing it a priori as a cognitio intuitiva, making it possible for humans to achieve happiness in statu viae. In contrast, in Ordinatio IV, dist. 49, Scotus emphasizes the value of beatitude in its ethical and theological sense, taking recourse to the Augustinian and Boethian definitions in order to understand its nature as the full expression of the intellective, volitional a... (shrink)

Purpose Given the considerable challenges posed by disinformation to both society and journalism, how do news media outlets in Hispanic America and Spain address this pervasive global phenomenon? The purpose of this study is to evaluate the extent to which these outlets embrace recommendations from academic, professional and institutional spheres for countering false contents. Design/methodology/approach A qualitative content analysis was used using variables linked to transparency, verification and potential errors incurred. This study comprehensively analyses the ethical codes of 34 digital (...) native outlets spanning 12 Hispanic American countries (Bolivia, Chile, Colombia, Cuba, Ecuador, Guatemala, Honduras, Mexico, Paraguay, Peru, Uruguay and Venezuela), as well as Spain. Findings The key findings reveal significant variations in adherence to the recommended guidelines. Particularly striking is the disparity between compliance with transparency and verification compared to notably higher adherence to measure aimed at rectifying errors. This exploratory study paves the way for further research on additional countries. Originality/value Ethical codes are a fundamental instrument of media accountability. Nevertheless, their utility in the fight against misinformation has barely been addressed. This study is pioneering in the field of disinformation and ethical codes within digital native media outlets in Hispanic America and Spain. (shrink)

This article carried out an analysis from the hermeneutical category of the symbol in the novel Blindness by José Saramago, following Paul Ricoeur, in which the symbols of sin, stain and guilt were chosen to be developed after defining the relevance and the impact of the category of analysis on current situations in our society. Making use not only of the texts referring to Ricoeur's hermeneutics, but also of The Symbolic of Evil, a conceptual journey is proposed to elucidate how (...) the senses and meanings of the symbols of evil are configured in our culture and, through this understanding, address the situation of the symbolic apparatus of Saramago's novel. Carrying out an analysis of these hermeneutical categories in a novel such as Blindness becomes the opportunity to show a different meaning and sense of a novel that has clearly shown its relevance in previous times and that today, in the middle of a pandemic, invites us to rethink that world and to face the fact of understanding our own blindness and the blindness of the world in the midst of a dizzying speed that requires us to assume our reality in another way. In the words of Ricoeur, the symbol gives food for thought and it is time for us to think through our own symbols about the reality that is presented to us in Saramago's novel and to extrapolate it to the realities that are configured every day in our Western world. (shrink)

El artículo propone demostrar que la sintaxis espacial de la escena entre Etéocles y el coro (vv. 78-368), atravesada por el género de lamento, constituye un mecanismo potente, dinámico y programático para involucrar y orientar a la audiencia en relación con la acción que se desarrolla, en un proceso que depende de la potencia del teatro en tanto espectáculo. Se sostiene que, en _Siete contra Tebas_, aquel personaje –individual o colectivo– que dispone sobre el espacio es quien tiene poder. En (...) la escena estudiada, la toma del espacio y la licencia para desplazarse en él se instalan como asunto fundamental. (shrink)

This paper examines undergraduate business students' perception of corporate social responsibility in cases in which they have not attended any specific course either dealing with CSR or providing training in ethics. A survey was conducted of 535 Spanish business students as future managers. The results show that the stakeholders' perspective deserves a huge attention for those students considering what the keys of business success are. Significant differences in perception were nevertheless identified when a multifactorial analysis was undertaken. Female students are (...) more concerned about CSR issues. The maximization of value for shareholders is less valued by second- and third-year students than by first-year ones. The findings point to a number of important orientations for the future development of university curriculum. (shrink)

Background: In the last decades, there have been important developments in the scientific and technological areas of healthcare. On certain occasions this provokes conflict between the patients' rights and the values of healthcare professionals which brings about, within this clinical relationship, the problem of conscientious objection. Aims: To learn the opinions that the Nurses of the Madrid Autonomous Community have regarding conscientious objection. Research design: Cross-cutting descriptive study. Participants and research context: The nurses of 9 hospitals and 12 Health Centers (...) in the Madrid Autonomous Community. The study was done by means of an auto completed anonymous questionnaire. The variables studied were social-demographical and their opinions about conscientious objections. Ethical considerations: The study was approved by the Ethical Community of Clinical Research of the University Hospital Príncipe de Asturias. Participants were assured of maximum confidentiality and anonymity. Findings: A total of 421 nurses answered the questionnaire. In total, 55.6% of the nurses confirmed they were religious believers, and 64.3% declared having poor knowledge regarding conscientious objection. The matters that caused the greatest objections were voluntary abortions, genetic embryo selection, refusal of blood transfusions, and therapy refusal. Discussion: Different authors state that the most significant cases of conscientious objections for health professionals are those regarding carrying out or assisting in abortions, euthanasia, the practice of assisted reproduction and, finally, the prescription and dispensing of the morning-after pill. In our study, the most significant cases in which the nurses would declare conscientious objections would be the refusal to accept treatment, the selection of embryos after genetic diagnosis preimplantation, the patient’s refusal to receive blood transfusions due to religious reasons and pregnant women’s request for voluntary abortions within the first 14 weeks. Conclusion: Nurses’ religious beliefs influence their opinions regarding conscientious objection. The nurses who declare themselves as religious believers object in a higher percentage than those without religious beliefs. (shrink)

In order to present the incidence of the dynamic turn in the logic of scientific research, we begin with a section, in this article, that deals with logical games as triggers of this dynamic turn in contemporary logic, together with the program of logical dynamics of information and interaction. We briefly introduce the main characteristics of the logic favorable to independence and the game-theoretical semantics, of dialogical logic, as well as the essential elements of this program. Although from any of (...) these points of view we have a list of logical tools to deal with more clearly epistemological issues, we highlight the role of dynamic epistemic logic, to which we dedicate the following section. There follows another one in which we enter the logical studies of abduction as one of the fundamental problems of contemporary epistemology and, in a new section, in terms of the theoretical constructs of the preceding sections, we present and explain a phenomenon that emerged in the field of linguistics, the case of the discovery of the Amazonian language pirahã, which should be considered an anomaly within the framework of the Chomskian theory. (shrink)

Little has been studied on the relationship between affect and school problems related with attendance. This study aims to identify different affective profiles and to determine whether these profiles differ from each other based on the four functional conditions of school refusal behavior. Participants comprised 1,816 Spanish adolescents aged 15–18 years. The Positive and Negative Affect Schedule for Children-Short Form and the School Refusal Assessment Scale-Revised for Children were administered. Latent profile analysis revealed five affective profiles: low affective profile, self-fulfilling (...) profile, low positive affect profile, self-destructive profile, and high affective profile. The self-destructive profile revealed the highest average scores in the first three factors of the SRAS-R-C, whereas the high affective profile reached the highest average score in the fourth factor. On the contrary, the self-fulfilling profile obtained the lowest average scores in the first two factors of the SRAS-R-C, whereas the low affective profile revealed the lowest average scores in the last two factors. Findings suggest the relevance of developing more adaptative affective profiles, such as the self-fulfilling profile, which would contribute to diminishing school attendance problems. (shrink)

RESUMEN El presente trabajo describe los cambios estratégicos del Centro de Inmunología y Productos Biológicos de la Universidad de Ciencias Médicas de Camagüey que contribuyen a la formación profesional, la investigación y los servicios científico técnicos. Recoge los resultados obtenidos desde el 2015 hasta el 2017. Los referentes teóricos permiten un acercamiento epistémico que facilita la relación con el conocimiento y la creación de concepciones para abordar los problemas de salud. El centro tiene cuatro proyectos asociados a programas y 11 (...) institucionales. Se posee 2,7 publicaciones por autor y 18 participaciones en eventos, de ellos, ocho internacionales. Se perfecciona un sistema de gestión de la calidad, nueve servicios científico-técnicos, diversos servicios a la docencia y proyectos de investigaciones. Se aprovecha el potencial que genera el proceso de auto-organización del trabajo colectivo, para un mejor funcionamiento, sinergia y sustentabilidad de la gestión de una unidad de desarrollo e innovación. ABSTRACT The present work describes the strategic changes of the Center of Immunology and Biological Products of the University of Medical Sciences of Camagüey that contributes to the professional training, the investigation and the technical-scientist services. It gathers the results obtained from 2015 to 2017. The theoretical bases allow an epistemic approach that facilitates the relation with the knowledge and the creation of conceptions to tackle the health problems. The center has four projects associated with programs and 11 institutional ones. There are possessed 2.7 publications per author and 18 participations in events, of them, eight international ones. Scientist - technical staff perfects a system of management of the quality, nine services, diverse services to the teaching and projects of investigations. One makes use of the potential that generates the auto-organization process of collective work, for a better functioning, synergy and sustainability of the management of a unit of development and innovation. (shrink)

Background: The high level of satisfaction of users of a health service is largely due to the fact that they receive excellent care from healthcare professionals. Compassionate care is an essential component of excellent care. But what do nurses understand compassion to be? Research objectives: To analyse the concept of compassion from the perspective of nurses in the Andalusian Public Health System, Spain. Research design: This is a qualitative study following the grounded theory model. Four focus groups and 25 in-depth (...) interviews were conducted. Participants and research context: A total of 68 nursing professionals working in the Andalusian Public Health System (Spain) participated. Theoretical sampling was used, with participants being recruited using the snowball technique. Ethical considerations: This research was approved by the Research Ethics Committee of the Centro-Almería Health District (CEICA 27/9/17). Findings: From the analysis of the data, four themes emerged that helped to understand the concept of compassion according to nurses: ‘Negative perception of the term compassion’, ‘Compassion and empathy as synonyms’, ‘Beyond empathy’, and ‘Effects of having a compassionate attitude’. Discussion: Nurses perceive the concept of compassion differently to each other and even contradictorily. This concept is imbued with cultural elements, which adds confusion to understanding it, and is even perceived as something negative similar to pity. Conclusion: Nurses confuse the concepts of empathy and compassion as if they were synonymous. Before considering training in compassion for healthcare professionals, it is essential to clarify the concept of compassion through educational interventions. (shrink)

Due to its allegedly diverse population and strong doctor–patient relations, Latin America has become one of the most attractive locations for international clinical trials. In the paper, I examine the case of recruitment of women and minority patients to serve as subjects of international clinical trials, through CROs operating in Latin America. In particular, the paper examines some of the strategies that CROs use to expand their services in the Latin American medical market, illuminating the mechanisms through which the current (...) organization of medical research contributes to power imbalances in the Global South. After analyzing the epistemic and ethical shortcomings of such endeavor, I show how Latin American patients participating in clinical trials are located in a position of double disadvantage. First, they suffer the consequences of a lack of appropriate understanding of symptoms and reaction to treatment. Second, they suffer the consequences of being subjects in clinical trials which are not designed to meet their needs, but the needs of patients in the Global North. Accordingly, I conclude by highlighting the importance of this double disadvantage and suggesting that the problem can be understood in terms of a misalignment of commercial, ethical, and epistemic concerns in clinical research. (shrink)

The article examines the process of niche standardization in medical research as an example of democratizing strategies implemented in industry-funded science. I argue that niche standardization can lead to undesirable epistemic and ethical consequences, if the various goals of research are not properly aligned. I examine two examples: the case of Sarafem, approved for the treatment of premenstrual dysphoric disorder in women, and the case of BiDil, approved for exclusive use in African Americans for the treatment of congestive heart failure. (...) I conclude by cautioning against the unqualified support of democratizing strategies in industry-funded research. (shrink)

The purpose of this paper is to uncover some of the limitations that critical contextual empiricism, and in particular Longino's contextualism, faces when trying to provide a normative account of scientific knowledge that is relevant to current scientific research. After presenting the four norms of effective criticism, I show how the norms have limited scope when dealing with cases of current scientific practices. I then present some historical evidence for the claim that the organization of science has changed in recent (...) decades, and I argue that the uncovered limitations emerge from this larger phenomenon. Finally, I conclude by suggesting two ways to overcome the previously uncovered limitations. (shrink)